Roguetheoryofsmellgetsaboost

1.Acontroversialtheoryofhowwesmell,whichclaimsthatourfinesenseofodourdependsonquantummechanics,hasbeengiventhethumbsupbyateamofphysicists.

2.CalculationsbyresearchersatUniversityCollegeLondon(UCL)showthattheideathatwesmellodourmoleculesbysensingtheirmolecularvibrationsmakessenseintermsofthephysicsinvolved.

3.That'sstillsomewayfromprovingthatthetheory,proposedinthemid-1990sbybiophysicistLucaTurin,iscorrect.Butitshouldmakeotherscientiststaketheideamoreseriously.

4."Thisisabigstepforward,"saysTurin,whohasnowsetuphisownperfumecompanyFlexitralinVirginia.Hesaysthatsincehepublishedhistheory,"ithasbeenignoredratherthancriticized."

5.Mostscientistshaveassumedthatoursenseofsmelldependsonreceptorsinthenosedetectingtheshapeofincomingmolecules,whichtriggersasignaltothebrain.Thismolecular'lockandkey'processisthoughttoliebehindawiderangeofthebody'sdetectionsystems:itishowsomepartsoftheimmunesystemrecogniseinvaders,forexample,andhowthetonguerecognizessometastes.

6.ButTurinarguedthatsmelldoesn'tseemtofitthispictureverywell.Moleculesthatlookalmostidenticalcansmellverydifferent—suchasalcohols,whichsmelllikespirits,andthiols,whichsmelllikerotteneggs.Andmoleculeswithverydifferentstructurescansmellsimilar.Moststrikingly,somemoleculescansmelldifferent—toanimals,ifnotnecessarilytohumans—simplybecausetheycontaindifferentisotopes(atomsthatarechemicallyidenticalbuthaveadifferentmass).

7.Turin'sexplanationforthesesmellyfactsinvokestheideathatthesmellsignalinolfactoryreceptorproteinsistriggerednotbyanodourmolecule'sshape,butbyitsvibrations,whichcanenourageanelectrontojumpbetweentwopartsofthereceptorinaquantum-mechanicalprocesscalledtunnelling.Thiselectronmovementcouldinitiatethesmellsignalbeingsenttothebrain.

8.Thiswouldexplainwhyisotopescansmelldifferent:theirvibrationfrequenciesarechangediftheatomsareheavier.Turin'smechanism,saysMarshallStonehamoftheUCLteam,ismorelikeswipe-cardidentificationthanakeyfittingalock.

9.Vibration-assistedelectrontunnellingcanundoubtedlyoccur—itisusedinanexperimentaltechniqueformeasuringmolecularvibrations."Thequestioniswhetherthisispossibleinthenose,"saysStoneham'scolleague,AndrewHorsfield.

10.StonehamsaysthatwhenhefirstheardaboutTurin'sidea,whileTurinwashimselfbasedatUCL,"Ididn'tbelieveit".But,headds,"becauseitwasaninterestingidea,IthoughtIshouldproveitcouldn'twork.Ididsomesimplecalculations,andonlythenbegantofeelLucacouldberight."NowStonehamandhisco-workershavedonethejobmorethoroughly,inapapersoontobepublishedinPhysicalReviewLetters.

11.TheUCLteamcalculatedtheratesofelectronhoppinginanosereceptorthathasanodorantmoleculeboundtoit.Thisratedependsonvariouspropertiesofthebiomolecularsystemthatarenotknown,buttheresearcherscouldestimatetheseparametersbasedontypicalvaluesformoleculesofthissort.

12.Thekeyissueiswhetherthehoppingratewiththeodorantinplaceissignificantlygreaterthanthatwithoutit.Thecalculationsshowthatitis—whichmeansthatodouridentificationinthiswayseemstheoreticallypossible.

13.ButHorsfieldstressesthatthat'sdifferentfromaproofofTurin'sidea."Sofarthingslookplausible,butweneedproperexperimentalverification.We'rebeginningtothinkaboutwhatexperimentscouldbeperformed."

14.Meanwhile,Turinispressingaheadwithhishypothesis."AtFlexitralwehavebeendesigningodorantsexclusivelyonthebasisoftheircomputedvibrations,"hesays."Oursuccessrateatodorantdiscoveryistwoordersofmagnitudebetterthanthecompetition."Attheveryleast,heisputtinghismoneywherehisnoseis.

Questions5-9

Completethesentencesbelowwithwordsfromthepassage.UseNOMORETHANTHREEWORDSforeachanswer.

5.Thehypothesisthatwesmellbysensingthemolecularvibrationwasmadeby______.

6.Turin'scompanyisbasedin______.

7.Mostscientistsbelievedthatournoseworksinthesamewayasour______.

8.Differentisotopescansmelldifferentwhen______weighdifferently.

9.AccordingtoAudrewHorsfield,itisstilltobeprovedthat______couldreallyoccurinhumannose.

-----Didyounoticehimcomein?

-----No.I________afootballgame.

Thesefiguresaregrossunderestimatesofthetrueincidenceofoccupationalill-health.

ThissignsinAmericarepresents:

Directions:Therearetenblanksinthefollowingpassage.YouarerequiredtochoosethebestonefromthegivenfourchoicesmarkedA,B,C,andD.Thenwritedownthecorrectanswerinthebrackets.Thissectiontotals10points,onepointforeachblank.

Beforemarketingyourselfglobally,itisimportantto1yourbusinessisreadytodealwithchallengespresentedbytheinternationalenvironment2

languageandculturalbarriers,foreignlaws,orderfulfillment,andpre/postsalessupport.

LanguageandCulture-Neithertechnicalaccuracy3perfecttranslationissufficientwhenconsideringthelanguageyouwillcommunicatethrough.Itisimportanttoreallyunderstandhowalanguageisusedbythepeopleinyour4market.

RegionalLaws-Allphasesofproduct5areaffectedbyregulations.Theproductitself,suchasitsphysicalandchemicalaspects,issubjecttolaws6

toprotectconsumerswithrespecttopurity,safetyorperformance.Productfeaturessuchaspackagingandwarranties,advertising,salespromotiontechniquesarealsosubjecttolocalregulations.

OrderFulfillment-Howwillyoudeliveryourproducts?Whatbusinesspartnerswillyouneedtoensuresmoothlogisticsofyourproduct?Canyouhandleyourshipmentcosts?Ifyoucannot7demandorensuresmoothdeliveryofyourproduct,youareatriskofnegativelyaffectingyourbusinessanditsimage.Itisimportanttofindandqualify8

distributors,andpayparticularattentiontocontractnegotiationanddistributionmanagement.

PreandPostSalesSupport-9withyourcustomersaswellasyourbusinesspartnersisanimportantconsiderationwhenmarketingandsellinginternationally.Manybusinessesareabletomeetcustomerexpectationsthroughstrategicalliancesorforeigndistributorswhodealwiththelocalcustomerbaseontheir10.

()1A.ensureB.assureC.reassureD.sure

()2A.excludingB.excludedC.includingD.included

()3A.soB.norC.andD.or

()4A.localB.ownC.targetD.home

()5A.salesB.exhibitionC.promotionD.development

()6A.plannedB.proposedC.supposedD.designed

()7A.meetB.runintoC.encounterD.face

()8A.potentB.politeC.ethicalD.potential

()9A.ConnectionB.CommunicationC.LinkD.Contact

()10A.accountB.partC.behalfD.market