newweapontofightcancer
1.Britishscientistsarepreparingtolaunchtrialsofaradicalnewwaytofightcancer,whichkillstumoursbyinfectingthemwithviruseslikethecommoncold.
2.Ifsuccessful,virustherapycouldeventuallyformathirdpillaralongsideradiotherapyandchemotherapyinthestandardarsenalagainstcancer,whileavoidingsomeofthedebilitatingside-effects.
3.LeonardSeymour,aprofessorofgenetherapyatOxfordUniversity,whohasbeenworkingonthevirustherapywithcolleaguesinLondonandtheUS,willleadthetrialslaterthisyear.CancerResearchUKsaidyesterdaythatitwasexcitedbythepotentialofProfSeymour’spioneeringtechniques.
4.Oneofthecountry’sleadinggeneticists,ProfSeymourhasbeenworkingwithvirusesthatkillcancercellsdirectly,whileavoidingharmtohealthytissue."Inprinciple,you’vegotsomethingwhichcouldbemanytimesmoreeffectivethanregularchemotherapy,"hesaid.
5.Cancer-killingvirusesexploitthefactthatcancercellssuppressthebody’slocalimmunesystem."Ifacancerdoesn’tdothat,theimmunesystemwipesitout.Ifyoucangetavirusintoatumour,virusesfindthemaverygoodplacetobebecausethere’snoimmunesystemtostopthemreplicating.Youcanregarditasthecancer’sAchilles’heel."
6.Onlyasmallamountofthevirusneedstogettothecancer."Theyreplicate,yougetamillioncopiesineachcellandthecellburstsandtheyinfectthetumourcellsadjacentandrepeattheprocess,"saidProfSeymour.
7.Preliminaryresearchonmiceshowsthatthevirusesworkwellontumoursresistanttostandardcancerdrugs."It’saninterestingpossibilitythattheymayhaveanadvantageinkillingdrug-resistanttumours,whichcouldbequitedifferenttoanythingwe’vehadbefore."
8.Researchershaveknownforsometimethatvirusescankilltumourcellsandsomeaspectsoftheworkhavealreadybeenpublishedinscientificjournals.Americanscientistshavepreviouslyinjectedvirusesdirectlyintotumoursbutthistechniquewillnotworkifthecancerisinaccessibleorhasspreadthroughoutthebody.
9.ProfSeymour’sinnovativesolutionistomaskthevirusfromthebody’simmunesystem,effectivelyallowingthevirusestodowhatchemotherapydrugsdo-spreadthroughthebloodandreachtumourswherevertheyare.Thebighurdlehasalwaysbeentofindawaytodelivervirusestotumoursviathebloodstreamwithoutthebody’simmunesystemdestroyingthemontheway.
10."Whatwe’vedoneismakechemicalmodificationstothevirustoputapolymercoataroundit-it’sastealthviruswhenyouinjectit,"hesaid.
11.Afterthestealthvirusinfectsthetumour,itreplicates,butthecopiesdonothavethechemicalmodifications.Iftheyescapefromthetumour,thecopieswillbequicklyrecognisedandmoppedupbythebody’simmunesystem.
12.Thetherapywouldbeespeciallyusefulforsecondarycancers,calledmetastases,whichsometimesspreadaroundthebodyafterthefirsttumourappears."There’sanawfulstatisticofpatientsinthewest...withmalignantcancers;75%ofthemgoontodiefrommetastases,"saidProfSeymour.
13.Twovirusesarelikelytobeexaminedinthefirstclinicaltrials:adenovirus,whichnormallycausesacold-likeillness,andvaccinia,whichcausescowpoxandisalsousedinthevaccineagainstsmallpox.Forsafetyreasons,bothwillbedisabledtomakethemlesspathogenicinthetrial,butProfSeymoursaidheeventuallyhopestousenaturalviruses.
14.Thefirsttrialswilluseuncoatedadenovirusandvacciniaandwillbedeliveredlocallytolivertumours,inordertoestablishwhetherthetreatmentissafeinhumansandwhatdoseofviruswillbeneeded.Severalmoreyearsoftrialswillbeneeded,eventuallyalsoonthepolymer-coatedviruses,beforethetherapycanbeconsideredforuseintheNHS.Thoughtheapproachwillbeexaminedatfirstforcancersthatdonotrespondtoconventionaltreatments,ProfSeymourhopesthatonedayitmightbeappliedtoallcancers.
Questions1-6
Dothefollowingstatementsagreewiththeinformationgiveninthereadingpassage?Forquestions1-6write
TRUEifthestatementagreeswiththeinformation
FALSEifthestatementcontradictstheinformation
NOTGIVENifthereisnoinformationonthisinthepassage
1.Virustherapy,ifsuccessful,hasanadvantageineliminatingside-effects.
2.CancerResearchUKisquitehopefulaboutProfessorSeymour’sworkonthevirustherapy.
3.Viruscankillcancercellsandstopthemfromgrowingagain.
4.Cancer’sAchilles’heelreferstothefactthatvirusmaystaysafelyinatumorandreplicate.
5.Toinfectthecancercells,agooddealofvirusesshouldbeinjectedintothetumor.
6.Researchesonanimalsindicatethatviruscouldbeusedasanewwaytotreatdrug-resistanttumors.
Question7-9
Basedonthereadingpassage,choosetheappropriateletterfromA-Dforeachanswer.
7.Informationaboutresearchesonviruseskillingtumorcellscanbefound
(A)onTV
(B)inmagazines
(C)oninternet
(D)innewspapers
8.Totreattumorsspreadingoutinbody,researcherstryto
(A)changethebody’immunesystem
(B)injectchemotherapydrugsintobloodstream.
(C)increasetheamountofinjection
(D)disguisethevirusesonthewaytotumors.
9.Whenthechemicalmodifiedvirusintumorreplicates,thecopies
(A)willsoonescapefromthetumorandspreadout.
(B)willbewipedoutbythebody’simmunesystem.
(C)willbeimmediatelyrecognizedbytheresearchers.
(D)willeventuallystopthetumorfromspreadingout.
Questions10-13
Completethesentencesbelow.Chooseyouranswersfromthelistofwords.Youcanonlyuseeachwordonce.
NBTherearemorewordsinthelistthanspacessoyouwillnotusethemall.
Inthefirstclinicaltrials,scientistswilltryto……10……adenovirusandvaccinia,soboththeviruseswillbelesspathogenicthanthe……11…….Theseuncoatedviruseswillbeapplieddirectlytocertainareastoconfirmsafetyonhumanbeingsandtheright……12……needed.Theexperimentswillfirstlybe……13……tothetreatmentofcertaincancers
1.答案：FALSE (见第2段：If successful, virus therapy could eventually form a third pillar alongside radiotherapy and chemotherapy in the standard arsenal against cancer, while avoiding some of the debilitating side-effects. Virus therapy 只能避免一些副作用，而不是根除。)
2.答案：TRUE (见第3段，特别是最后一句： Cancer Research UK said yesterday that it was excited by the potential of Prof Seymour’s pioneering techniques. )
3. 答案：NOT GIVEN (文中没有提到virus可以抑制肿瘤细胞再生长)
4. 答案：TRUE (见第5段第3、4句： 这里“cancer’s Achilles’ heel”指 “If you can get a virus into a tumour, viruses find them a very good place to be because there’s no immune system to stop them replicating.” Achilles’ heel的意思是“唯一致命弱点”)
5. 答案：FALSE (见第6段第第1句：Only a small amount of the virus needs to get to the cancer.)
6. 答案：TRUE (见第7段：Preliminary research on mice shows that the viruses work well on tumours resistant to standard cancer drug. ……, which could be quite different to anything we’ve had before." )
7. 答案：B (见第8段第1、2句：Researchers have known for some time that viruses can kill tumour cells and some aspects of the work have already been published in scientific journals. Journal意思是“日报、期刊、杂志”)
8. 答案：D (见第9段第1句：Prof Seymour’s innovative solution is to mask the virus from the body’s immune system, …… “mask”的意思是“掩盖、隐蔽、伪装”， 在这里和 “disguise”同义。)
9. 答案：B (见第11段第2句： If they escape from the tumour, the copies will be quickly recognised and mopped up by the body’s immune system.. “mop up”这里与 “wipe out” 同义，意思是“消灭、歼灭”。)
10.答案：disable (见第13段最后1句：For safety reasons, both will be disabled to make them less pathogenic in the trial, but Prof Seymour said he eventually hopes to use natural viruses. )
11. 答案：natural ones (见第13段最后1句：For safety reasons, both will be disabled to make them less pathogenic in the trial, but Prof Seymour said he eventually hopes to use natural viruses. )
12. 答案：dosage (见第14段第1句：The first trials will use uncoated adenovirus and vaccinia and will be delivered locally to liver tumours, in order to establish whether the treatment is safe in humans and what dose of virus will be needed.)
13. 答案：directed (见第14段最后1句：Though the approach will be examined at first for cancers that do not respond to conventional treatments, …)
暂无解析
-----Wouldyoumindmyusingyourpen?
-----_______________.
Isthere______________totellus?No,nothing.
To begin with,"muzak"(音乐广播网 )was intended simplyto createasoothing(安慰)atmosphere.Recently,however,it's ecome big business —thanks in part to recentresearch.Dr.Ronald Milliman,an American marketing expert,hasshown that music can boost sales or increase factory roduction by as much as a third.But,it has to be light music.A fast one has no effect atall on sales.Slow music can increase receipts by 38%.This isprobably because shoppers slow down and have more opportunityto spot items they like to buy.Yet,slow music isn't alway sanswer.Dr.Milliman found,for example,that in restaurants slowmusic meant customers took longer to eat their meals,whichreduced overall sales.So restaurants owners might be welladvised to play up-tempo music to keep the customers moving—unless of course,the resulting indigestion leads tocomplaints!
练习：
1.The reason why background music is so popular isthat ______.
A.it can have a powerful effect on those who hear it
B.it can help to create a soothing atmosphere
C.it can boost sales or increase factory production erywhere
D.it can make customers eat their meals quickly
2.Background music means ________.
A.light music that customers enjoy mostB.fast music that makes people move fast
C.slow music that can make customers enjoy their meals
D.the music you are listening to while you are doingomething
3.Restaurant owners complain about background musicbecause ______.
A.it results in indigestion
B.it increases their sales
C.it keeps customers moving
D.it decreases their sales
4.The word"up-tempo music"probably means_____.
A.slow music
B.fast music
C.light music
D.classical music
-----AheavysnowhitmostofthepartsofChinainJanuary,2008.
-----____________terriblenews!
1. A European spacecraft took off today to spearhead the search for another "Earth" among the stars.
2. The Corot space telescope blasted off aboard a Russian Soyuz rocket from the Baikonur cosmodrome in Kazakhstan shortly after 2.20pm.
3. Corot, short for convection rotation and planetary transits, is the first instrument capable of finding small rocky planets beyond the solar system. Any such planet situated in the right orbit stands a good chance of having liquid water on its surface, and quite possibly life, although a leading scientist involved in the project said it was unlikely to find "any little green men".
4. Developed by the French space agency, CNES, and partnered by the European Space Agency (ESA), Austria, Belgium, Germany, Brazil and Spain, Corot will monitor around 120,000 stars with its 27cm telescope from a polar orbit 514 miles above the Earth. Over two and a half years, it will focus on five to six different areas of the sky, measuring the brightness of about 10,000 stars every 512 seconds.
5. "At the present moment we are hoping to find out more about the nature of planets around stars which are potential habitats. We are looking at habitable planets, not inhabited planets. We are not going to find any little green men," Professor Ian Roxburgh, an ESA scientist who has been involved with Corot since its inception, told the BBC Radio 4 Today programme.
6. Prof Roxburgh said it was hoped Corot would find "rocky planets that could develop an atmosphere and, if they are the right distance from their parent star, they could have water".
7. To search for planets, the telescope will look for the dimming of starlight caused when an object passes in front of a star, known as a "transit". Although it will take more sophisticated space telescopes planned in the next 10 years to confirm the presence of an Earth-like planet with oxygen and liquid water, Corot will let scientists know where to point their lenses.
8. Measurements of minute changes in brightness will enable scientists to detect giant Jupiter-like gas planets as well as small rocky ones. It is the rocky planets - that could be no bigger than about twice the size of the Earth - which will cause the most excitement. Scientists expect to find between 10 and 40 of these smaller planets.
9. Corot will also probe into stellar interiors by studying the acoustic waves that ripple across the surface of stars, a technique called "asteroseismology".
10. The nature of the ripples allows astronomers to calculate a star’s precise mass, age and chemical composition.
11. "A planet passing in front of a star can be detected by the fall in light from that star. Small oscillations of the star also produce changes in the light emitted, which reveal what the star is made of and how they are structured internally. This data will provide a major boost to our understanding of how stars form and evolve," Prof Roxburgh said.
12. Since the discovery in 1995 of the first "exoplanet" - a planet orbiting a star other than the Sun - more than 200 others have been found by ground-based observatories.
13. Until now the usual method of finding exoplanets has been to detect the "wobble" their gravity imparts on parent stars. But only giant gaseous planets bigger than Jupiter can be found this way, and they are unlikely to harbour life.
14. In the 2010s, ESA plans to launch Darwin, a fleet of four or five interlinked space telescopes that will not only spot small rocky planets, but analyse their atmospheres for signs of biological activity.
15. At around the same time, the US space agency, Nasa, will launch Terrestrial Planet Finder, another space telescope designed to locate Earth-like planets.
Choose the appropriate letter from A-D for question 1.
1. Corot is an instrument which
(A) can help to search for certain planets
(B) is used to find planets in the orbit
(C) can locate planets with human beings
(D) can spot any planets with water.
Do the following statements agree with the information given in the reading passage? For questions 2-5 write
TRUE if the statement agrees with the information
FALSE if the statement contraicts the information
NOT GIVEN if there is no information on this in the passage
2. Scientists are trying to find out about the planets that can be inhabited.
3. BBC Radio 4 recently focuses on the broadcasting of Corot.
4. Passing objects might cause a fall in light.
5. Corot can tell whether there is another Earth-like planet.
Based on your reading of the passage, complete the sentences below with words taken from the passage. Use NO MORE THAN THREE WORDS for each answer.
With measurements, scientists will be able to search for some gaseous and rocky planets. They will be extremely excited if they can discover some small 6. __________, the expected number of which could be up to 7. __________ .
Corot will enable scientists to study the 8. __________ of stars. In this way, a star’s mass, age and chemical composition can be calculated.
According to Prof Roxburgh, changes in light can be caused by passing planets or star 9. __________. The related statistics can gain us a better 10. __________ of the star formation and evolvement.
Observatories have found many exoplanets, which are 11. __________ other stars than the Sun. The common way used in finding exoplanets can only detect huge gas planets, which do not 12. ___________ .
With the launching of Darwin, astronomers will be able to analyse whether those rocky planets have 13. __________ for life.