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试述风湿病的基本病理变化

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正确答案:

风湿病分三期:

1、变质渗出期:病变的结缔组织发生粘液变性、纤维素样坏死;伴有少量的炎细胞浸润本期约持续1个月。

2.增生期:病变部位形成梭形风湿小体,其中央为纤维素样坏死灶,周围聚集数量不等风湿细胞,外围有少量成纤维细胞、淋巴细胞和单核细胞,本期约持续2~3个月。

3.纤维化期(愈合期),风湿小体的纤维化.风湿细胞成纤维细胞转化为瘢痕组织.此期约持续2~3个月

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